Tag: pharmaceutical procurement

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Top Trends in the Pharmaceutical Excipients Market

The pharmaceutical industry is constantly innovating and developing new drugs to combat diseases and improve drug efficacy. Active ingredients and excipients are two components that play a significant role in the drug development process. Pharmaceutical excipients are an inert additive substance which is used in the drug development process to carry the active drug to a particular part of the body, disintegrate drug into smaller particles, and to improve the medicine flavor. Pharmaceutical excipients are broadly categorized as per their functionality into binders and fillers, coating agent, disintegrants, flavoring agents, colorants, preservatives, and lubricants. Procurement experts from SpendEdge estimate a healthy growth rate 5.99% for this market owing to rise of generics and biosimilars manufacturing. The report also outlines APAC region to register the fastest growth rate because of the low cost of material, easy availability of cost-effective workforce, and presence of untapped resources in terms of manufacturing capabilities.

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Growth of Biologics and Biosimilars

Manufacturing biologics is a complicated task as they are susceptible to minor changes. Manufacturers need to overlook the manufacturing process right from start to end carefully. In order to get desired outcomes, the pharma industry’s demand for pharmaceutical excipients is on the rise due to the growth of biologics and biosimilars. For instance, excipients that can mitigate the biological production risks and improve the production yield when using specific formulation technique are in high demand.

Shifting Focus in the APAC Region

APAC region has been identified as the fastest growing market for pharmaceutical products due to rising income levels and willingness to spend on modern healthcare. Additionally, manufacturers are also looking to shift their production facilities to this region due to lower cost and lax government policies. Consequently, the growth of pharma industry in this region has directly led to the growth in the pharmaceutical excipients market. For instance, in 2016, Ashland opened a pharmaceutical excipient plant in China for capturing the increasing regional demand for modern formulation technologies.

Use of Nanotechnology

Nanotechnology refers to the manipulation of matter with size less than a nanometer with varied applications in surface science, semiconductors, molecular engineering, and microbiology. In recent times, nanotechnology is increasingly being used in the pharma industry as it improves API solubility, medicine stability, enhances the pharmacological activity with targeted delivery. The emergence of such technologies is urging the pharma manufacturers to develop new techniques to enhance the capability of excipients.

Use in Identification of Counterfeit Medicines

The flow of counterfeit medicines in the market has been troubling the drug manufacturers and drug authorities for a very long time. Counterfeit medicines pose a serious health threat to the consumer, so it must be dealt with care by the concerned authorities. For instance, in 2015, the INTERPOL seized over 20 million fake and illicit medicinal drugs, with an estimated value of over US$80 million, circulating in the open market. In order to facilitate identification of counterfeit medicines, drug manufacturers include pharmaceutical excipients in the drugs. Consequently, the use of such excipients is also reducing the overall cost of testing the authenticity of medicines.

Read more about the trends in the pharmaceutical excipients market along with medicine formulation development, category management, strategic purchasing, pricing insights, and negotiation strategy in SpendEdge’s upcoming report on the global pharmaceutical excipients market.

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Top Trends in the Pharmaceutical Analytical Testing Services Market

The rising cost of drug development process has urged pharmaceutical companies to look out for ways to reduce the overall cost and time. The pharma industry turns towards highly specialized contract research organizations (CROs) who depict expertise in drug discovery assistance, regulatory compliance, lead identification, clinical data management, consultation, clinical trials, and project management. Pharmaceutical analytical testing is one of the research support services rendered by CROs and contract laboratories to pharmaceutical manufacturers. These organizations use various processes to analyze the intermediate drug ingredients and final drugs, so that the quality of the medication can be ensured. Toxicological risk assessments, environmental monitoring, clinical and non-clinical bioanalysis, stability testing, method validation, preclinical research, and biological assay development are some of the services under pharmaceutical analytical testing. The procurement market intelligence report predicts a healthy growth rate of 7.71% for the pharmaceutical testing market.

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Capability Enhancement Toward Analytical Testing of Biosimilars

Numerous drugs in the pharma industry are nearing the end of their patent lifetime. This has led pharmaceutical companies to divert their attention to biosimilars from biologics. Such move has motivated pharmaceutical testing companies to enhance their capabilities in the analytical testing of biosimilars. Compatibility studies for biosimilars, stability testing, product release testing, and protein analysis of biosimilars are some of the capabilities suppliers have been focusing. Consequently, enhancement of such capabilities reduces the risks associated with drug development.

Rising Demand from Nutraceuticals Industry

Traditionally, the pharmaceutical testing services were availed mainly by the pharmaceutical companies. However, today that trend looks to be slowly changing as nutraceuticals industry is also emerging as an active consumer of these services. This surge in demand can be attributed to increasing regulations for nutraceutical manufacturing companies demanding them to get their raw materials tested for quality and conduct release testing for their products.

Adoption of FTE-based Contracts

Since a long time, pharmaceutical testing service providers have been charging their clients on a per contract or per sample basis. Such pricing strategy is slowly changing as suppliers are looking to charge their clients on FTE-based contracts irrespective of workload, compound, or analytical technique used. The supplier allocates a dedicated team during the tenure of the project and manages the project resources along with the client. Such contracts ensure that the dedicated team members acquire a strong knowledge of the procedures and requirements of the project leading to fewer errors and higher consistency in the output.

Technological Advancements in Analytical Testing Equipment

The pharma industry is pressurizing pharmaceutical testing companies to reduce the testing time for drug ingredients forcing the suppliers to use advanced equipments and processes. For the same reason, the majority of the suppliers are now using HRAM instruments that allow users to identify the target molecule confidently. Additionally, several suppliers are now actively using morphologically-directed Raman spectroscopy, which is based on a combination of Ramana spectroscopy and automated imaging. Use of advanced equipment eliminates the need to perform multiple trials and subsequently increases the reliability and accuracy of pharmaceutical testing.

Read more about the trends in the pharmaceutical testing market along with sourcing strategies, pricing insights, top pharmaceutical analytical testing service providers, procurement challenges, and pricing models in SpendEdge’s upcoming report on the global pharmaceutical analytical testing services market.

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Top 5 CRO Companies to Depend on for Drug Development

Typically, the cost of developing a drug costs pharmaceutical companies millions of dollars and sometimes even touching the billion dollar market. The development process goes through multiple stages which can last about 10-12 years. In the changing economy, pharmaceutical companies have to look for ways to control such costs and ensure compliance against stringent regulations. As a result, the pharma industry is looking to outsource the drug development process to Contract Research Organization (CRO) companies. CRO companies partner with various drug companies and thereby gather vast experiences in conducting clinical trials and testing out the efficacy of the new drug. CRO service providers offer services including drug discovery assistance, clinical data management, consultation, regulatory compliance, lead identification, clinical trials, and project management. The recent procurement market intelligence report on global pharmaceutical drug development services market estimates the market to grow at a rate of 7.35% during the forecast period.

Request Free SampleTop CRO Companies to Watch Out

IQVIA

IQVIA, formerly known as Quintiles IMS Holdings, is one of the leading CRO companies involved in the field of biopharmaceutical development and outsourcing services alongside depicting expertise in healthcare database and analytical services. The company is the world’s largest contract research organization and specializes in phase II-IV trials. The company was formed as a result of the merger between Quintiles Transnational and IMS Health in 2016. It is also the world’s largest CRO company based on market revenue with the company posting revenues of US$6.87 billion in 2016.

LabCorp

LabCorp is an American company and one of the leading CRO companies in the world. Currently, with close to 40 clinical laboratories in the US, it has one of the largest networks of clinical labs in the world. With more than 50,000 employees serving more than 220,000 clients across 60 countries, the company generated revenues of US$9.43 billion in 2016. The company is the pioneer in the field of using polymerase chain technology for genomic technology and also exhibits expertise in oncology trials, HIV genotyping, and phenotyping.

PAREXEL

PAREXEL is a world-renowned life sciences consulting firm that helps pharma companies develop approximately 95% of the 200 top-selling biopharmaceuticals on the market. Leading pharma companies such as Catalent Inc, Merck & Co. Inc., Pfizer Inc., ICON plc, and GlaxoSmithKline plc all depend on PARAXEL for new drug development. In June 2017, the company announced that it is set to be acquired by Pamplona Capital for US$5 billion.

ICON

ICON is a global provider of outsourced drug development services depicting expertise in the field of late phase services. In fact, it is the world’s second-largest player in the field of late phase services in terms of market share. Their services range from clinical, consulting, and commercial services, which incorporate trial design and full study execution. The company is renowned for its exceptional quality management system subjected to more than 1,700 successful audits by buyers, regulatory bodies, and ISO. They also offer knowledge, software, and systems for adaptive trials.

INC Research

INC Research is one of the leading CRO companies known for ‘The Trusted Process,’ a proprietary trial management methodology developed by the company. The company recently merged its operations with inVentive Health to expand the global scale and add capabilities. Their key services include early phase trials, phase II and III trials, late phase trials, consulting, and clinical monitoring.

Read more about the top CRO companies along with CRO services, clinical trials, drug development, pricing strategy, procurement challenges, and supplier evaluation criteria in SpendEdge’s upcoming report on the global pharmaceutical drug development services market.

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The Biggest Problems with Pharmaceutical Raw Materials Market, And How You Can Fix It

If you were to ever glance on the packaging of medicines, it would enlist the chemicals and composition used to manufacture that drug. However, chemicals are not the only raw material used in the pharmaceutical manufacturing process. Pharmaceutical raw materials also include natural raw materials like leaves, flowers, fruits, fungi, and seeds, in addition to synthetic materials and biologics. Pharmaceutical raw materials are classified into three groups namely active pharmaceutical ingredients (APIs), intermediaries, and additives. The pharmaceutical industry relies heavily on chemical suppliers and biologics manufacturers for their pharmaceutical supplies. The pharmaceutical industry has been witnessing stable growth with higher growth prospects in emerging regions such as the APAC, which is expected to grow at a CAGR of nearly 9%-10% by 2021. (SpendEdge Procurement Market Intelligence Report – Bulk Drug Raw Materials Market) Although the growth prospects look promising for the pharmaceutical industry, suppliers of pharmaceutical raw materials have been facing tough challenges that affect their growth.

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Top Challenges in the Pharmaceutical Raw Materials Market

Threat from Counterfeit Products

Falsified medicines or counterfeit drug products can easily enter the pharma supply chain across the world. Counterfeit drugs, usually contain low-quality APIs, wrong ingredient, or even the incorrect dosages. Such counterfeit products are then fraudulently mislabeled without compliance with intellectual property rights and can cause side-effects and other complexities when consumed. Pharmaceutical raw materials manufacturers will be negatively affected by such acts. As a result, medicine surveillance services and fake -identification technologies such as mass spectrometry (MS), infra-red (FTIR) spectroscopy, nuclear magnetic resonance (NMR) spectroscopy, Raman spectroscopy, and gas chromatography-mass spectrometry (GC-MS) are gaining prominence.

Increase in Trade Taxes

Manufacturing hubs of the final drug products are located in the primary markets such as the US and Europe. However, these companies procure pharmaceutical raw materials from emerging countries like Brazil, China, India, and Israel. The problem arises when drug manufacturers have to incur additional expenses in the form of trade taxes and customs expenses. To promote “Made in America” movement, the Trump administration has slapped a double-digit tariff for companies outsourcing drug manufacturing activities. Such regulations will discourage drug manufacturers to obtain pharmaceutical raw materials at a lower cost.

Increase in Regulatory Delays

Drugs and medicines being a sensitive matter regarding public health, are heavily regulated by governments and medical associations. Pharmaceutical raw materials suppliers, therefore, must obtain approval from regulatory bodies such as FDA and EMA to bring the final products to the market. Delays in the approval process can slow down the time-to-market, and risk expiry of patent validity along with other operational issues. Such delays severely affect the drug manufacturers profitability, thereby hindering the overall growth of the market.

Read more about the top challenges in the pharmaceutical raw materials market along with competitive landscape analysis, contract and SLA terms, pricing strategies, sourcing strategy, and procurement market intelligence in SpendEdge’s upcoming report on the global beef market.

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Top 4 Trends Driving the Productivity of Pharmaceutical Supply Chain

It is very characteristic of a pharma company to invest millions of dollars in new drug development with very little success rate. They then face pressure from governments and consumers to keep the prices of such medicines low for it to be accessible to everyone. Consequently, pharma companies are looking for new ways to increase their revenue stream and improve efficiency in every aspect of their business. Innovations in pharma procurement along with advancements in technology can significantly boost profitability in the pharma industry and provide them a competitive advantage.SE_Demo2

Current Trends in Pharmaceutical Industry

Reinvesting in R&D Process

For a very long time, big pharma players in this industry were relying on old techniques and technology for drug discovery. Since companies started using big data analytics, they have significantly improved their success rates for drug discovery. Additionally, using real-world evidence has equipped them to speed up the drug discovery process, decrease R&D costs, and improve time-to-market.

Resource Reallocation in the Emerging Markets

The pharma industry has been shifting its focus from developed nations to emerging markets as the growth curve in the developed parts of the world continues to flatten. The emerging markets which are relatively underserved have a vast growth potential for key suppliers in the pharma industry. The suppliers are exploring ways to increase the efficiency of the pharmaceutical supply chain by identifying potential locations for developing and manufacturing medicines. For instance, the developed parts of the world are looking at the Asian and Latin American region to outsource the process of clinical research.

New Modes of Healthcare Delivery

Hospitals and healthcare specialists are driving up the overall cost of healthcare. Companies are looking for ways to cut down costs and improve outcomes by trying to reduce reliance on hospitals and specialists. The recent advancements in medicines along with technological advancements such as fitness tracker and health monitoring devices has made self-medication and telemedicine possible. Such disruption in the pharmaceutical supply chain could significantly improve the costs, efficiency, and profitability of the pharma industry.

Increasing Emphasis on Outcomes

The increasing emphasis on outcomes is the most prominent pharma trend currently. Majority of the players in the pharma industry are modifying their existing models such as a fee for service models in favor of outcome-based models. Such measures help reduce wastages and fraud mostly in the healthcare reimbursement sector. The pharmaceutical supply chain needs to be highly active by closely supervising and monitoring the value delivery process to the patients in order to improve outcomes.

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Improving Efficiency in Pharma Manufacturing Through IoT Technologies

The unprecedented power of the Internet of Things (IoT) has urged a vast majority of the companies in the manufacturing sector to make use of this technology to unlock limitless potential. Pharmaceutical manufacturing companies are no exception to this, as IoT has the potential to revolutionize all aspects of the pharmaceutical manufacturing process from drug discovery to manufacturing. IoT in pharma manufacturing coupled with big data and advanced analytics can scrutinize massive amounts of data that can be harnessed to improve manufacturing efficiency.SE_Demo2

IoT in Pharma Manufacturing

Connected Equipment

Pharma manufacturing companies rely heavily on batch manufacturing and equipment is usually self-contained. So it requires men and materials to move constantly on the shop floor. Although industrial automation and control technologies are widely used, real-time status of equipment is not readily accessible to make informed decisions that can improve equipment effectiveness. IoT technology can assist to maintain the safety and efficacy of drug products by maintaining specific storage condition and providing extended visibility into shop-floor activities.

Real-Time Visibility into Warehouse Operations

Warehousing is a critical component for every pharmaceutical manufacturing companies. Shortage of certain medicines can have serious consequences, on the other hand overstocking can lead to product wastages and higher inventory holding costs. Since pharma companies maintain numerous warehouses spread across vast geographies, warehousing operations amount for a vast majority of the pharma logistics cost. Smart warehouses can increase real-time visibility into the operations by tracking products in the warehouse and optimally utilize operators and transport equipment. IoT technology is essential in pharma supply chain as it can report inconsistencies, optimize warehouse floor space, and monitor storage of sensitive medicines.

Controlling Cold Chain Conditions

Pharmaceutical manufacturers need to be very careful while handling biologics, which are highly sensitive to storage conditions. Such biologics are high-value items with shorter shelf lives carrying strict temperature requirements. IoT technology makes it possible to remotely monitor the condition of the drug and ensure that ambient temperature is maintained at temperature-controlled containers.

Remote Fleet Management

Use of digital technology such as GPS systems can allow remote monitoring of the transport process and ensure shipment visibility throughout the supply chain. A multitude of data regarding vehicle location, vehicle performance, and view of the driver can be collected which can be processed and decisions to optimize fleet management can be taken remotely. Consequently, it can drastically reduce the time-to-market, prevent product spoilage, and lower carrying costs.

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Industry Best Practices Benchmarking Study helps Disposable Syringes Manufacturer Formulate Better Negotiation Strategies

Category Overview

Lately, the pharmaceutical industry has witnessed astonishing growth due to the increase in the demand for long-acting formulations and devices with lower adverse effects and high efficacy. According to our industry best practices specialists, it has been noted that the pharmaceutical industry is facing substantial operational and economic challenges. As a result, many pharmaceutical firms have started adopting industry best practices studies to make the most of the opportunities and gain a stronger foothold this market space.

The industry best practices benchmarking studies offered by SpendEdge help pharmaceutical industry players adopt best-in-class procurement and sourcing strategies.

The Procurement Pain Point and Insights Offered

A leading pharmaceutical industry player wanted to identify peer group companies and their key suppliers. Additionally, the client also wanted to cut down costs by implementing a best-in-class and efficient procurement process. Furthermore, they also wanted to assess their peer group company’s success stories and approach towards innovation.request free proposal

The industry best practices specialists at SpendEdge carried out a blended research methodology, which included primary and secondary research coupled with qualitative and quantitative data collection methodologies to cater to the specific category requirements of the client.

During the course of this industry best practices benchmarking study, the pharmaceutical industry client specializing in disposable syringes was provided with a list of the peer group companies and their key suppliers. The list provided helped the client identify the key drivers to enhance their procurement process. Additionally, the client was also able to optimize their techniques and implement an efficient procurement process.

Key questions answered in this industry best practices study include

pharmaceutical industryBusiness Outcome

This industry best practices benchmarking study helped the pharmaceutical industry client implement best-in-class procurement and sourcing strategies. Additionally, the client was able to formulate a better negotiation strategy with their suppliers. As a result, the leading pharmaceutical industry player specializing in disposable syringes was able to cut down their overall costs.

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Sourcing of Pharmaceutical Supplies: A Best Practices Study by SpendEdge

Category Overview

The global pharmaceutical packaging industry is rapidly growing due to the use of biodegradable materials as it adds to the sustainability of the packaging through all the stages of the pharmaceutical supplies lifecycle. However, the unpredictability in the price of the raw materials used in this industry may pose a significant challenge to the key market stakeholders.

The Procurement Pain Point and Insights Offered

A global pharmaceutical products company wanted to cut down the costs of the goods associated with pharmaceutical supplies. Furthermore, they also wanted to incorporate the best practices and consolidate their procurement strategies with suppliers from different countries. The client also wanted to streamline their existing procurement process for pharmaceutical supplies and identify potential cost saving opportunities.

SpendEdge carried out an in-depth research process consisting of primary and secondary research methodologies coupled with qualitative and quantitative data collection methods to cater to the specific category requirements of the client. Furthermore, theRequest Free Proposal suppliers were also graded based on the standards and allotted weights. The final supplier selection was carried out on parameters including geographic coverage, qualitative assessment scores, previous experience with the vendors, and product development and tooling costs. Moreover, we collaborated our research with a huge database of exclusive resources such as industry journals and reports, white papers, and news articles. The best practices study on the sourcing of pharmaceutical supplies also helped gain a better understanding of the procurement best practices for pharmaceutical supplies and the vital service offerings of the medical suppliers.

Business Outcome

This best practices study on the sourcing of pharmaceutical supplies helped the client identify and reduce the list of the major suppliers offering pharmaceutical packing solutions. This list offered by SpendEdge also helped the client achieve better high-cost savings compared to the current spend. Additionally, material cost indexing and steady conversion costs were also negotiated.

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Procurement Market Intelligence Helps a Pharmaceutical Company

The Procurement Pain Point

A leading pharma company with a global presence approached SpendEdge to engage in a procurement market intelligence study to gain insights on supplier selection and management for integrated facilities SE-Integratedmanagement services. The study helped the client understand the perceived risks in an IFM engagement, risk mitigation strategies, and the various cost saving opportunities. Furthermore, this study helped the client analyze the cost structure, pricing models, service level agreement (SLA) aspects, and the perceived risks in an integrated facility management engagement.

To gain a comprehensive understanding of procurement best practices, SpendEdge’s team of market intelligence experts followed an integrated research methodology consisting of primary and secondary research followed by discussion with category experts to get a detailed overview of the current category procurement strategies, supply and demand market insights, and the best practices in supplier selection. In addition, research experts also provided insights on the assessment of pricing and supplier engagement models and carried out a gap assessment to identify the key areas of improvement.

Procurement Insights Offered and the Outcome

To address the requirements specific to the needs of the client, we deployed a SE-Integrated2team of FTE analysts with expertise in procurement services and domain expertise. The process helped the client gain detailed insights on risk compliance and regulatory environment and strategize based on the best benchmarking standards in the industry. The analysts followed a blended research methodology to offer category-specific insights to understand the vendor capability and the supplier reach analysis.

In just five weeks, the client identified cost saving opportunities through assessment of the procurement best practices and improvement areas in the specific category. Additionally, the study also helped the client with improved supplier selection and management methodologies, supplier negotiations, and successful implementation of procurement market intelligence strategy for the vital spend areas, and capitalized on supplier performance through implementation of supplier relationship management. SE-Integrated3

This procurement market intelligence case study offers information on how we helped a pharmaceutical company with supplier selection and management. 

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Prominence of Supply Market in Pharmaceutical: Procurement Market Intelligence

Pharmaceutical companies are probing for new tactics to improve efficiency and to raise revenue in every business area exploring new markets, product lines, and sales channels. Ensuring regulatory compliance and creating global supply chain transparency are the main focus and challenge for the pharmaceutical firms. Additionally, Pharmaceutical companies face a significant challenge in maintaining a strong supplier relationship. The innovative and reliable procurement strategies essentially for supply chain management of the legal services in the pharmaceutical industry gives a competitive advantage for the vendors in the market.

One of the major pharmaceutical firm with a wide range of products for several diseases – approached SpendEdge to commission a supply market intelligence engagement to help them understand the supply landscape for legal services and improve their ability to benchmark current services and pricing and to help the client in shortlisting the top suppliers based on their capabilities and understand the average pricing levels.

The Procurement Pain Points; Obstacles perceived by SpendEdge Analysts

The foremost challenge for a pharmaceutical industry is to ensure regulatory compliance during the process of product development. Pharmaceutical firms are dealt with curing the diverse human diseases through their vast line of medicines and drugs, thus it creates a strong point for the firms to maintain the quality of medicines and ensure the usage of relevant ingredients in the process of manufacturing and these ingredients are supplied by diverse suppliers.

Pharmaceutical firms include a wide range of products in their portfolio leading to a complicated situation in terms of category planning and management. Category management involves pricing, quality management, information, enticing promotion of each of the medicine and drug products.

Additionally, pharmaceutical firms face an immense challenge in shortlisting the top suppliers of legal services. Pharmaceutical firms are compelled to utilize a documented practice for supplier selection to reduce risk during the process of manufacturing the medicines. A detailed review of the supplier’s overall capabilities is required time to time.

Solutions Offered by SpendEdge

The well-designed process, proper material, and supplier selection are the initiating steps of a reliable supply chain in the pharmaceutical industry. These qualities are sustained through on-going stewardship of the client-supplier relationship resulting in a satisfactory business arrangement where each company can expect many years of successful business dealings.

This category procurement market intelligence study by SpendEdge helps the client in shortlisting the top suppliers based on their capabilities and understand the average pricing levels. Our Solutions are not limited to determining the appropriate and capable suppliers, it also provides an in-depth understanding of the overall supply landscape that helps pharmaceutical firms to improve their ability to benchmark current services and pricing.

SpendEdge employed a team of procurement intelligence specialists with expertise in legal services category who identified and acquired information from various reliable sources and developed category-specific insights that helped the client’s procurement teams with category planning and category management.

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